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Peptide record

TPDB61395

POD Cell-penetrating Peptides standard
36 amino acids
Basic Information
3D PDB MODEL
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TPDB61395
POD
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 MLCPP 2.0 Peptipedia
standard
No
A 36-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, MLCPP 2.0, and Peptipedia, with an available 3D structural model.
C-terminal: Conjugation with nanoparticle N-terminal: Conjugation with rhodamine B
Sequence
CGGGARKKAAKAARKKAAKAARKKAAKAARKKAAKA
Physicochemical Analysis
C153H288N60O37S1
NDEQHILMFPSTWYV
A
3592.41
12.46
16
0
16
+16
12.19
-0.964
44.44
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
16
A
4
R
0
N
0
D
1
C
0
E
0
Q
3
G
0
H
0
I
0
L
12
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 16 R: 4 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 0 K: 12 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
36
C153H288N60O37S1
3592.41
12.46
+16
12.19
-0.964
Conjugation with nanoparticle
L
Cationic
Linear
Conjugation with rhodamine B
N[C@@H](CS)C(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Assay & Model

New Zealand white rabbits
New Zealand white rabbits

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Protein derived
Nanoparticle
In vivo
CCCHHHHCTHHHHHHHHHHHHHHHHHHHHTTTCCCC
Additional Detail Fields 1 fields
CCCHHHHCTHHHHHHHHHHHHHHHHHHHHTTTCCCC