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Peptide record

TPDB61389

DPV15b Cell-penetrating Peptides standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB61389
DPV15b
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 23-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
Sequence
CGAYDLRRRERQSRLRRRERQSR
Physicochemical Analysis
C119H211N55O35S1
NHIKMFPTWV
R
3004.39
12.23
10
3
4
+7
12.33
-2.343
38.26
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
1490
49.59
6
Residue Composition
number
1
A
10
R
0
N
1
D
1
C
2
E
2
Q
1
G
0
H
0
I
2
L
0
K
0
M
0
F
0
P
2
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 10 N: 0 D: 1 C: 1 E: 2 Q: 2 G: 1 H: 0 I: 0 L: 2 K: 0 M: 0 F: 0 P: 0 S: 2 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
23
C119H211N55O35S1
3004.39
12.23
+7
12.33
-2.343
L
Linear
N[C@@H](CS)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa, PC-3, NCI-H460 and MDA-MB-231

Source & Reference

CPPsite3.0
CPPsite3
US 20090186802

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Nucleic acid (siRNA)
Cytoplasm
Endocytic pathway
In vitro
CTTCSSSHHHHHHHHHTTTTTCC
Additional Detail Fields 1 fields
CTTCSSSHHHHHHHHHTTTTTCC