Back to search

Peptide record

TPDB61374

Alexa488-Melan-A-polyLys (control peptide) Cell-penetrating Peptides standard
20 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB61374
Alexa488-Melan-A-polyLys (control peptide)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 20-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, MLCPP 2.0, Peptipedia, and other sources, with an available 3D structural model.
Sequence
CELAGIGILTVKKKKKQKKK
Physicochemical Analysis
C101H189N29O25S1
RNDHMFPSWY
K
2241.85
10.74
8
1
6
+7
8.60
-0.730
97.50
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
1
A
0
R
0
N
0
D
1
C
1
E
1
Q
2
G
0
H
2
I
2
L
8
K
0
M
0
F
0
P
0
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 1 E: 1 Q: 1 G: 2 H: 0 I: 2 L: 2 K: 8 M: 0 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
20
C101H189N29O25S1
2241.85
10.74
+7
8.60
-0.730
Free
L
Cationic
Linear
Free
N[C@@H](CS)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

DCs, HUVECs and Jurkat cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Synthetic
Fluorophore (Alexa488) and Protein (ovalbumin)
Lower efficiency than Tat peptide
In vitro
CCCSSCCCCCSSGGGGSCCC
Additional Detail Fields 1 fields
CCCSSCCCCCSSGGGGSCCC