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Peptide record

TPDB61360

S-TAT Cell-penetrating Peptides standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB61360
S-TAT
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 13-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, MLCPP 2.0, Peptipedia, and other sources, with an available 3D structural model.
N-terminal: Cysteine addition
Sequence
CAYGGQQGGQGGG
Physicochemical Analysis
C44H66N16O18S1
RNDEHILKMFPSTWV
G
1139.16
5.32
0
0
2
-0
0.46
-0.792
7.69
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
1490
130.80
5
Residue Composition
number
1
A
0
R
0
N
0
D
1
C
0
E
3
Q
7
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 1 E: 0 Q: 3 G: 7 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
13
C44H66N16O18S1
1139.16
5.32
-0
0.46
-0.792
L
Cationic
Linear
Cysteine addition
N[C@@H](CS)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)NCC(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)N)C(=O)NCC(=O)NCC(=O)N[C@@H](CCC(=O)N)C(=O)NCC(=O)NCC(=O)NCC(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

BCECs and C6s cells

Assay & Model

Mice
Mice

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Synthetic
Nanoparticle (Liposomes)
Endocytosis
In vitro and in vivo
CCCCCCCCCCCCC
Additional Detail Fields 1 fields
CCCCCCCCCCCCC