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Peptide record

TPDB61353

CALNNTat Cell-penetrating Peptides standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB61353
CALNNTat
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 17-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
CALNNGRKKRRQRRRPQ
Physicochemical Analysis
C85H157N41O22S1
DEHIMFSTWYV
R
2137.50
12.71
8
0
2
+8
8.33
-2.512
28.82
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
5
Residue Composition
number
1
A
6
R
2
N
0
D
1
C
0
E
2
Q
1
G
0
H
0
I
1
L
2
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 6 N: 2 D: 0 C: 1 E: 0 Q: 2 G: 1 H: 0 I: 0 L: 1 K: 2 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
17
C85H157N41O22S1
2137.50
12.71
+8
8.33
-2.512
Free
L
Cationic
Linear
Free
N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Human Skin And Dorsal Skin From Newborn Hairless Mice

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Chimeric
Gold nanoparticle and Nanorods
Penetrated the skin in larger numbers (2–6 times) than only nanoparticle
Ex vivo
CCCCCCEETTEECTTCC
Additional Detail Fields 1 fields
CCCCCCEETTEECTTCC