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Peptide record

TPDB61303

pAntpHD 50A Cell-penetrating Peptides standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB61303
pAntpHD 50A
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 26-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, Peptipedia, and other sources, with an available 3D structural model.
N-terminal: Conjugation with fluorescein
Sequence
AYALCLTERQIKIWFANRRMKWKKEN
Physicochemical Analysis
C150H238N44O36S2
DGHPSV
K
3297.93
10.62
7
2
12
+5
3.50
-0.815
71.54
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
12490
378.72
6
Residue Composition
number
3
A
3
R
2
N
0
D
1
C
2
E
1
Q
0
G
0
H
2
I
2
L
4
K
1
M
1
F
0
P
0
S
1
T
2
W
1
Y
0
V
Amino Acid Distribution
A: 3 R: 3 N: 2 D: 0 C: 1 E: 2 Q: 1 G: 0 H: 0 I: 2 L: 2 K: 4 M: 1 F: 1 P: 0 S: 0 T: 1 W: 2 Y: 1 V: 0
Chemical Descriptors
26
C150H238N44O36S2
3297.93
10.62
+5
3.50
-0.815
Free
L
Amphipathic
Linear
Conjugation with fluorescein
N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)N)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Rat embryonic neurons

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Protein derived
Fluorophore (fluorescein)
Cytoplasm and nucleus
In vitro
CCTTCCCTTTSCSCCTTSCCTTTSCC
Additional Detail Fields 1 fields
CCTTCCCTTTSCSCCTTSCCTTTSCC