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Peptide record

TPDB61300

P2 (SmacN7–Arg8) Cell-penetrating Peptides standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB61300
P2 (SmacN7–Arg8)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 17-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation Chemical: SmacN7
Sequence
AVPIAQKGGRRRRRRRR-NH2
Physicochemical Analysis
C85H161N43O19
NDCEHLMFSTWY
R
2089.49
13.25
9
0
4
+9
7.94
-1.971
51.76
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
2
A
8
R
0
N
0
D
0
C
0
E
1
Q
2
G
0
H
1
I
0
L
1
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 8 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 2 H: 0 I: 1 L: 0 K: 1 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
17
C85H161N43O19
2089.49
13.25
+9
7.94
-1.971
Amidation
SmacN7
L
Linear
Free
N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

U266 Mm Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
FITC at N terminal via Ahx linker
In vitro
CCSSSSSSGGGSCC
Additional Detail Fields 1 fields
CCSSSSSSGGGSCC