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Peptide record

TPDB61294

PTD (Hph-1-GAL4) Cell-penetrating Peptides standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB61294
PTD (Hph-1-GAL4)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 10-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Gal4 Dna-Binding Domain (Dbd) conjugated
Sequence
ARVRRRGPRR
Physicochemical Analysis
C51H98N28O11
NDCEQHILKMFSTWY
R
1279.52
13.10
6
0
2
+6
5.22
-2.300
39.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
1
A
6
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
0
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 6 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
10
C51H98N28O11
1279.52
13.10
+6
5.22
-2.300
Gal4 Dna-Binding Domain (Dbd) conjugated
L
Cationic and amphipathic
Linear
Free
N[C@@H](Cc1ccccc1)C(=O)/N=C/C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HUVECs Cells

Assay & Model

5-week-old female mice (C57BL/6N)
5-week-old female mice (C57BL/6N)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic and amphipathic
Protein derived
HIF1A factor (pDNA)
High expression levels of HIF1A and HIF1A target gene
In vitro and in vivo
CCTTSSCCCCC
Additional Detail Fields 1 fields
CCTTSSCCCCC