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Peptide record

TPDB61293

Inv8 Cell-penetrating Peptides standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB61293
Inv8
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 32-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
N-terminal: Free (peptide coated FITC labelled microspheres)
Sequence
ARTINAQQAELDSALLAAAGFGNTTADVFDRG
Physicochemical Analysis
C139H222N42O49
CHKMPWY
A
3265.54
3.97
2
4
15
-2
4.37
-0.031
82.81
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
8
Residue Composition
number
8
A
2
R
2
N
3
D
0
C
1
E
2
Q
3
G
0
H
1
I
3
L
0
K
0
M
2
F
0
P
1
S
3
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 8 R: 2 N: 2 D: 3 C: 0 E: 1 Q: 2 G: 3 H: 0 I: 1 L: 3 K: 0 M: 0 F: 2 P: 0 S: 1 T: 3 W: 0 Y: 0 V: 1
Chemical Descriptors
32
C139H222N42O49
3265.54
3.97
-2
4.37
-0.031
Free
L
Linear
Free (peptide coated FITC labelled microspheres)
N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Nanoparticle [(FITC)-labeled latex microspheres]
Cytoplasm and nucleus membrane
Low (relative to Inv3)
In vitro
CCCCCTTTHHHHHHHHHHHTTSCSSTTTTCCC
Additional Detail Fields 1 fields
CCCCCTTTHHHHHHHHHHHTTSCSSTTTTCCC