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Peptide record

TPDB61275

Des1R Cell-penetrating Peptides standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB61275
Des1R
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 20-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
ARDNRRTRIWPRHLQLAVRN
Physicochemical Analysis
C108H182N44O27
CEGKMFSY
R
2528.91
12.70
7
1
7
+5
5.51
-1.375
83.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
5500
217.48
4
Residue Composition
number
2
A
6
R
2
N
1
D
0
C
0
E
1
Q
0
G
1
H
1
I
2
L
0
K
0
M
0
F
1
P
0
S
1
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 6 N: 2 D: 1 C: 0 E: 0 Q: 1 G: 0 H: 1 I: 1 L: 2 K: 0 M: 0 F: 0 P: 1 S: 0 T: 1 W: 1 Y: 0 V: 1
Chemical Descriptors
20
C108H182N44O27
2528.91
12.70
+5
5.51
-1.375
Free
L
Linear
Free
N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

E. Coli Strain Carolina #25922

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Higher arginine content improved translocation for DesHDAP6
In vitro
CCCCCSSSSCCGGGSSSSCC
Additional Detail Fields 1 fields
CCCCCSSSSCCGGGSSSSCC