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Peptide record

TPDB61259

Q8A Cell-penetrating Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB61259
Q8A
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 12-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation N-terminal: Conjugated with Cyanine5.5 (Cy5.5)
Sequence
APWHLSSAYSRT-NH2
Physicochemical Analysis
C62H90N18O18
NDCEQGIKMFV
S
1375.51
9.88
2
0
5
+1
-0.94
-0.600
49.17
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
6990
508.18
5
Residue Composition
number
2
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
0
I
1
L
0
K
0
M
0
F
1
P
3
S
1
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 2 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 0 L: 1 K: 0 M: 0 F: 0 P: 1 S: 3 T: 1 W: 1 Y: 1 V: 0
Chemical Descriptors
12
C62H90N18O18
1375.51
9.88
+1
-0.94
-0.600
Amidation
L
Linear
Conjugated with Cyanine5.5 (Cy5.5)
N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)O)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

H9C2 Cells And Human Bronchial Epithelial Cells(Cfbe41O-)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Cy5.5 dye
In vitro
CCCSSSSCCCC
Additional Detail Fields 1 fields
CCCSSSSCCCC