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Peptide record

TPDB61253

YY25R1 Cell-penetrating Peptides standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB61253
YY25R1
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 37-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
APPLPPRNRGEDASPRELRRYYRSLRHYLNLVTRQRY
Physicochemical Analysis
C201H321N69O54
CIKMFW
R
4568.19
11.56
10
3
12
+6
10.77
-1.454
65.95
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
5960
130.47
10
Residue Composition
number
2
A
9
R
2
N
1
D
0
C
2
E
1
Q
1
G
1
H
0
I
5
L
0
K
0
M
0
F
5
P
2
S
1
T
0
W
4
Y
1
V
Amino Acid Distribution
A: 2 R: 9 N: 2 D: 1 C: 0 E: 2 Q: 1 G: 1 H: 1 I: 0 L: 5 K: 0 M: 0 F: 0 P: 5 S: 2 T: 1 W: 0 Y: 4 V: 1
Chemical Descriptors
37
C201H321N69O54
4568.19
11.56
+6
10.77
-1.454
Free
L
Linear
Free
N[C@@H](CCSC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CS)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Ai9 Tdtomato Npcs

Assay & Model

Ai9 or wild-type mice
Ai9 or wild-type mice

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
SpyCas9 RNPs
In vitro and in vivo
CCCSCCCCSSSTTTSSCCSSCSSCC
Additional Detail Fields 1 fields
CCCSCCCCSSSTTTSSCCSSCSSCC