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Peptide record

TPDB61215

Cell-penetrating Peptides Tumor-homing Peptides standard
34 amino acids
Basic Information
3D PDB MODEL
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TPDB61215
Cell-penetrating Peptides Tumor-homing Peptides
Cancer-related peptides Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP TumorHoPe2.0
standard
No
A 34-aa standard natural multi-activity (Cell-penetrating Peptides and Tumor-homing Peptides) peptide sequence curated from CellPPD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
Sequence
AKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKK
Physicochemical Analysis
C166H289N53O44
NCGHIMFTWY
K
3731.45
11.31
12
3
8
+9
19.54
-1.712
37.65
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
6
A
3
R
0
N
1
D
0
C
2
E
1
Q
0
G
0
H
0
I
1
L
9
K
0
M
0
F
8
P
2
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 6 R: 3 N: 0 D: 1 C: 0 E: 2 Q: 1 G: 0 H: 0 I: 0 L: 1 K: 9 M: 0 F: 0 P: 8 S: 2 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
34
C166H289N53O44
3731.45
11.31
+9
19.54
-1.712
CendR
Evidence Records 2 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell, Tumor vessel, Tumor stem cell, Endothelial cell,
Homing
gC1q/p32 receptor

Source & Reference

TumorHoPe2.0
TumorHoPe2
Targeted delivery system and methods of use therefor
2022
US 11512110 B2
US 11512110 B2

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Athymic nude mice, ApoE null mice
Phage display library
T7 phage / cyclic Cx7C and linear X7 peptide library
Nanoworms(NWs), polyethylene glycol
Evidence 2 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell, Tumor vessel, Tumor stem cell, Endothelial cell,
Homing
gC1q/p32 receptor

Source & Reference

TumorHoPe2.0
TumorHoPe2
Targeted delivery system and methods of use therefor
2022
US 11512110 B2
US 11512110 B2

Other

Athymic nude mice, ApoE null mice
Phage display library
T7 phage / cyclic Cx7C and linear X7 peptide library
Nanoworms(NWs), polyethylene glycol
Additional Detail Fields 3 fields
Nanoworms(NWs), polyethylene glycol
Athymic nude mice, ApoE null mice
T7 phage / cyclic Cx7C and linear X7 peptide library