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Peptide record

TPDB61211

LinTT1 Cell-penetrating Peptides Tumor-homing Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB61211
LinTT1
Cell-penetrating Peptides Tumor-homing Peptides
Cancer-related peptides Delivery and barrier-penetrating peptides
CPPsite3.0 TumorHoPe2.0
standard
No
A 9-aa standard natural multi-activity (Cell-penetrating Peptides and Tumor-homing Peptides) peptide sequence curated from CPPsite3.0 and TumorHoPe2.0, with an available 3D structural model.
Sequence
AKRGARSTA
Physicochemical Analysis
C36H68N16O12
NDCEQHILMFPWYV
A
917.04
12.41
3
0
3
+3
2.38
-1.044
33.33
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
3
A
2
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
0
L
1
K
0
M
0
F
0
P
1
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 0 S: 1 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
9
C36H68N16O12
917.04
12.41
+3
2.38
-1.044
CendR
Evidence Records 3 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell, Endothelial cell
Homing
Breast cancer
p32/gC1qR

Source & Reference

TumorHoPe2.0
TumorHoPe2
Tumor-Penetrating Nanosystem Strongly Suppresses Breast Tumor Growth
2017
Shweta Sharma et al. Nano Lett. 2017 Mar 8 17(3):1356-1364.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
MCF10CA1a breast cancer cells
Phage Display Library
Iron oxide nanoparticles (nanoworms), D[KLAKLAK]2 pro-apoptotic peptide
Evidence 2 Activity

Activity

Tumor-homing Peptides

Target

Homing

Source & Reference

TumorHoPe2.0
TumorHoPe2
2023
De-Ping Wang et al. Acta Biomater. 2023 Sep 15:168:551-564.

Other

human H-chain ferritin (HFtn), AIE luminogens (AIEgens)
Evidence 3 Activity

Activity

Tumor-homing Peptides

Target

Endothelial cell, Tumor cell, Tumor vessel, Macrophage
Homing
Glioblastoma
p32

Source & Reference

TumorHoPe2.0
TumorHoPe2
Peptide-guided nanoparticles for glioblastoma targeting
2019
Säälik P et al. J Control Release. 2019 Aug 28:308:109-118.

Other

oxide nanoworms (NWs), albumin-paclitaxel nanoparticles
Additional Detail Fields 2 fields
Iron oxide nanoparticles (nanoworms), D[KLAKLAK]2 pro-apoptotic peptide human H-chain ferritin (HFtn), AIE luminogens (AIEgens) oxide nanoworms (NWs), albumin-paclitaxel nanoparticles
MCF10CA1a breast cancer cells