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Peptide record

TPDB61210

DPV3A Cell-penetrating Peptides standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB61210
DPV3A
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 16-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: DsRed & J-DsRed
Sequence
AKKRRRESRKKRRRES
Physicochemical Analysis
C85H163N41O23
NDCQGHILMFPTWYV
R
2127.49
12.53
11
2
1
+9
13.76
-3.369
6.25
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
1
A
7
R
0
N
0
D
0
C
2
E
0
Q
0
G
0
H
0
I
0
L
4
K
0
M
0
F
0
P
2
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 7 N: 0 D: 0 C: 0 E: 2 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 4 M: 0 F: 0 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
16
C85H163N41O23
2127.49
12.53
+9
13.76
-3.369
Free
DsRed & J-DsRed
L
Linear
Free
N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Huh-7 cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
DsRed dye
Cytosol
2% of DPV3A-DsRed and 7% of DPV3A-J-DsRed transduce into cells with 40 μg/mL
Macropinocytosis
In vitro
CCSSCCCCSCCCCSSCCCCC
Additional Detail Fields 1 fields
CCSSCCCCSCCCCSSCCCCC