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Peptide record

TPDB61204

AKH-αR5W4 Cell-penetrating Peptides standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB61204
AKH-αR5W4
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 14-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: NBD or Rhodamine B
Sequence
AKHKGRRWWRRWWR
Physicochemical Analysis
C97H141N37O15
NDCEQILMFPSTYV
R
2065.43
13.01
8
0
5
+7
-0.57
-2.550
7.14
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
22000
1065.16
0
Residue Composition
number
1
A
5
R
0
N
0
D
0
C
0
E
0
Q
1
G
1
H
0
I
0
L
2
K
0
M
0
F
0
P
0
S
0
T
4
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 0 L: 0 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 4 Y: 0 V: 0
Chemical Descriptors
14
C97H141N37O15
2065.43
13.01
+7
-0.57
-2.550
Free
NBD or Rhodamine B
L
Linear
Free
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa And Pc12 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Cu(II)
Cytosol
AKH-αR5W4(RhodB) entry was greater than AKH-αR5W4(NBD) after 5 min
Endocytosis
In vitro
CCCCCCCCC
Additional Detail Fields 1 fields
CCCCCCCCC