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Peptide record

TPDB61188

pAntpHD Cell-penetrating Peptides standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB61188
pAntpHD
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 26-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
N-terminal: Conjugation with fluorescein
Sequence
AHALCLTERQIKIWFQNRRMKWKKEN
Physicochemical Analysis
C149H239N47O36S2
DGPSYV
K
3328.95
10.95
8
2
10
+5
6.15
-1.092
67.69
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
11000
330.43
6
Residue Composition
number
2
A
3
R
2
N
0
D
1
C
2
E
2
Q
0
G
1
H
2
I
2
L
4
K
1
M
1
F
0
P
0
S
1
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 3 N: 2 D: 0 C: 1 E: 2 Q: 2 G: 0 H: 1 I: 2 L: 2 K: 4 M: 1 F: 1 P: 0 S: 0 T: 1 W: 2 Y: 0 V: 0
Chemical Descriptors
26
C149H239N47O36S2
3328.95
10.95
+5
6.15
-1.092
Free
L
Amphipathic
Linear
Conjugation with fluorescein
N[C@@H](C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)N)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Rat embryonic neurons

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Protein derived
Fluorophore (fluorescein)
Cytoplasm and nucleus
In vitro
CCSSCCGGGCCCCCTTCCCSSCCCC
Additional Detail Fields 1 fields
CCSSCCGGGCCCCCTTCCCSSCCCC