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Peptide record

TPDB61163

PF14K-CR6G Cell-penetrating Peptides modified_plain modified
22 amino acids
Basic Information
3D PDB MODEL
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TPDB61163
PF14K-CR6G
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
modified_plain
Yes
A 22-aa modified cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation Chemical: 5(6)-Carboxyrhodamine 6G at additional lysine on N terminal N-terminal: Stearylation
Sequence
AGYLLGKLLOOLAAAALOOLLK-NH2
Physicochemical Analysis
C88H154N20O20
RNDCEQHIMFPSTWV
L
1812.31
10.20
2
0
14
+2
-4.27
1.341
164.55
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
1490
82.22
1
Residue Composition
number
5
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
0
I
8
L
2
K
0
M
0
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 5 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 8 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
22
C88H154N20O20
1812.31
10.20
+2
-4.27
1.341
Amidation
5(6)-Carboxyrhodamine 6G at additional lysine on N terminal
Modified
Cationic and amphipathic
Linear
Stearylation
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

U87-Luc Glioblastoma And Pc12 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear Modified Cationic and amphipathic
Synthetic
Cy5-siRNA
Plasma Membrane
In vitro