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Peptide record

TPDB61159

TP14 Cell-penetrating Peptides standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB61159
TP14
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 19-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
N-terminal: Biotinylation at amino group of Lys
Sequence
AGYLLGKLKALAALAKKIL
Physicochemical Analysis
C94H167N23O21
RNDCEQHMFPSTWV
L
1955.50
10.64
4
0
13
+4
-1.48
0.979
170.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
1490
76.20
1
Residue Composition
number
5
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
1
I
6
L
4
K
0
M
0
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 5 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 1 L: 6 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
19
C94H167N23O21
1955.50
10.64
+4
-1.48
0.979
Free
L
Amphipathic
Linear
Biotinylation at amino group of Lys
N[C@@H](C)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Human bowes melanoma cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Chimeric
Biotin
Cytoplasm and nucleus and intracellular membranous structures
Lower than Transportan
Non-receptor mediated endocytosis
In vitro
CCSSSHHHHHHHHHHTTCC
Additional Detail Fields 1 fields
CCSSSHHHHHHHHHHTTCC