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Peptide record

TPDB61152

Transportan 10 Cell-penetrating Peptides standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB61152
Transportan 10
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 24-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, MLCPP 2.0, Peptipedia, and other sources, with an available 3D structural model.
Chemical: Linker Di-Glycine
Sequence
AGYLLGKINLKALAALAKKILGGC
Physicochemical Analysis
C111H195N29O27S1
RDEQHMFPSTWV
L
2400.01
10.31
4
0
14
+4
-1.59
0.888
150.83
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
1490
62.08
3
Residue Composition
number
5
A
0
R
1
N
0
D
1
C
0
E
0
Q
4
G
0
H
2
I
6
L
4
K
0
M
0
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 5 R: 0 N: 1 D: 0 C: 1 E: 0 Q: 0 G: 4 H: 0 I: 2 L: 6 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
24
C111H195N29O27S1
2400.01
10.31
+4
-1.59
0.888
Free
Linker Di-Glycine
L
Amphipathic
Linear
Free
N[C@@H](C)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)NCC(=O)N[C@@H](CS)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HT-29-luc cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Chimeric
PNA
Endocytosis
In vitro
CCCCSSCCCHHHHHHHHHTTTTTC
Additional Detail Fields 1 fields
CCCCSSCCCHHHHHHHHHTTTTTC