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Peptide record

TPDB61150

NF17 Cell-penetrating Peptides standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB61150
NF17
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 21-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation N-terminal: Stearylation
Sequence
AGYLLGKENLKALAALAKKIL-NH2
Physicochemical Analysis
C103H180N26O26
RDCQHMFPSTWV
L
2198.72
10.31
4
1
13
+3
0.96
0.552
153.81
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
1490
67.77
2
Residue Composition
number
5
A
0
R
1
N
0
D
0
C
1
E
0
Q
2
G
0
H
1
I
6
L
4
K
0
M
0
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 5 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 2 H: 0 I: 1 L: 6 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
21
C103H180N26O26
2198.72
10.31
+3
0.96
0.552
Amidation
L
Amphipathic
Linear
Stearylation
N[C@@H](C)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa, U87-Mg, N2A And Ht1084

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Synthetic
Cy5-labled pDNA
Nucleus
Endocytosis
In vitro
CCCCCCSSCTTIIIIITTTCC
Additional Detail Fields 1 fields
CCCCCCSSCTTIIIIITTTCC