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Peptide record

TPDB61137

biotinyl-CP8 Cell-penetrating Peptides standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB61137
biotinyl-CP8
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 16-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation Chemical: Fmoc-Lys(biotin)−OH was linked with the C-terminus N-terminal: Biotinylation
Sequence
AETVESCLAKPHTENK-NH2
Physicochemical Analysis
C73H121N21O27S1
RDQGIMFWY
E
1756.95
5.40
3
3
4
-1
9.21
-0.919
55.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
5
Residue Composition
number
2
A
0
R
1
N
0
D
1
C
3
E
0
Q
0
G
1
H
0
I
1
L
2
K
0
M
0
F
1
P
1
S
2
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 1 E: 3 Q: 0 G: 0 H: 1 I: 0 L: 1 K: 2 M: 0 F: 0 P: 1 S: 1 T: 2 W: 0 Y: 0 V: 1
Chemical Descriptors
16
C73H121N21O27S1
1756.95
5.40
-1
9.21
-0.919
Amidation
Fmoc-Lys(biotin)−OH was linked with the C-terminus
L
Linear
Biotinylation
N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

B16, Cos7, And HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
FITC-labeled Avidin
In vitro
CCHIIIIITCCCSCC
Additional Detail Fields 1 fields
CCHIIIIITCCCSCC