Peptide record

TPDB61135

Inv5 Cell-penetrating Peptides standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB61135
Inv5
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 26-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
C-terminal: Conjugated with TAMRA Chemical: Lys side chain amine at the C-terminus
Sequence
AEKVDPVKLNLTLSAAAEALTGLGDK
Physicochemical Analysis
C115H198N30O39
RCQHIMFWY
AL
2625.01
4.56
3
4
12
-1
7.26
0.100
116.54
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
4
Residue Composition
number
5
A
0
R
1
N
2
D
0
C
2
E
0
Q
2
G
0
H
0
I
5
L
3
K
0
M
0
F
1
P
1
S
2
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 5 R: 0 N: 1 D: 2 C: 0 E: 2 Q: 0 G: 2 H: 0 I: 0 L: 5 K: 3 M: 0 F: 0 P: 1 S: 1 T: 2 W: 0 Y: 0 V: 2
Chemical Descriptors
26
C115H198N30O39
2625.01
4.56
-1
7.26
0.100
Conjugated with TAMRA
Lys side chain amine at the C-terminus
L
Hydrophobic
Linear
Free
N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

By-2 Cells Leaves Of Nicotiana Benthamiana, Arabidopsis Thaliana, Tomato (Solanum Lycopersicum), Poplar (Hybrid Aspen Populus Tremula×Tremuloides Line T89), And Rice (Oryza Sativa).

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Hydrophobic
TAMRA dye
In vitro
CCCCBTTBCCCCSTTTHHHHHTCSCC
Additional Detail Fields 1 fields
CCCCBTTBCCCCSTTTHHHHHTCSCC