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Peptide record

TPDB61130

Inv9 Cell-penetrating Peptides standard
30 amino acids
Basic Information
3D PDB MODEL
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TPDB61130
Inv9
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia
standard
No
A 30-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
N-terminal: Free (peptide coated FITC labelled microspheres)
Sequence
ADVFDRGGPYLQRGVADLVPTATLLDTYSP
Physicochemical Analysis
C144H223N37O46
NCEHIKMW
DL
3208.58
3.87
2
4
13
-2
3.50
-0.067
91.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
2980
92.88
7
Residue Composition
number
3
A
2
R
0
N
4
D
0
C
0
E
1
Q
3
G
0
H
0
I
4
L
0
K
0
M
1
F
3
P
1
S
3
T
0
W
2
Y
3
V
Amino Acid Distribution
A: 3 R: 2 N: 0 D: 4 C: 0 E: 0 Q: 1 G: 3 H: 0 I: 0 L: 4 K: 0 M: 0 F: 1 P: 3 S: 1 T: 3 W: 0 Y: 2 V: 3
Chemical Descriptors
30
C144H223N37O46
3208.58
3.87
-2
3.50
-0.067
Free
L
Linear
Free (peptide coated FITC labelled microspheres)
N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Nanoparticle [(FITC)-labeled latex microspheres]
Cytoplasm and nucleus membrane
Low (relative to Inv3)
In vitro
CCSSCSSSSGGGTCTTCCCCCSCCCSSSCC
Additional Detail Fields 1 fields
CCSSCSSSSGGGTCTTCCCCCSCCCSSSCC