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Peptide record

TPDB61126

B1 Cell-penetrating Peptides standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB61126
B1
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 Peptipedia
standard
No
A 23-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0 and Peptipedia, with an available 3D structural model.
Sequence
ACSSSPSKHCGGGGRRRRRRRRR
Physicochemical Analysis
C100H183N53O28S2
NDEQILMFTWYV
R
2640.01
12.70
11
0
1
+10
9.60
-2.052
4.35
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
125
4.73
6
Residue Composition
number
1
A
9
R
0
N
0
D
2
C
0
E
0
Q
4
G
1
H
0
I
0
L
1
K
0
M
0
F
1
P
4
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 9 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 4 H: 1 I: 0 L: 0 K: 1 M: 0 F: 0 P: 1 S: 4 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
23
C100H183N53O28S2
2640.01
12.70
+10
9.60
-2.052
Free
L
Linear
Free
N[C@@H](C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CS)C(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

C166-eGFP cells

Source & Reference

CPPsite3.0
CPPsite3
WO 2011/020188 A1

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Nucleic acid (siRNA)
In vitro
CCCSSCCSSSSCSGGGGTTCCC
Additional Detail Fields 1 fields
CCCSSCCSSSSCSGGGGTTCCC