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Peptide record

TPDB61125

TD F4 Blood-Brain Barrier Cell-penetrating Peptides standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB61125
TD F4
Blood-Brain Barrier Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
BBPpredict Peptipedia CPPsite3.0 PerseuCPP
standard
No
A 11-aa standard natural multi-activity (Blood-Brain Barrier and Cell-penetrating Peptides) peptide sequence curated from BBPpredict, Peptipedia, CPPsite3.0, and other sources, with an available 3D structural model.
Sequence
ACSSSPSKHCG
Physicochemical Analysis
C40H66N14O16S2
RNDEQILMFTWYV
S
1063.17
8.30
2
0
1
+1
2.28
-0.500
9.09
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
125
11.76
6
Residue Composition
number
1
A
0
R
0
N
0
D
2
C
0
E
0
Q
1
G
1
H
0
I
0
L
1
K
0
M
0
F
1
P
4
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 1 H: 1 I: 0 L: 0 K: 1 M: 0 F: 0 P: 1 S: 4 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
11
C40H66N14O16S2
1063.17
8.30
+1
2.28
-0.500
Free
L
Linear
Free
N[C@@H](C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CS)C(=O)NCC(=O)O
Evidence Records 2 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

C166-eGFP cells

Source & Reference

CPPsite3.0
CPPsite3
WO 2011/020188 A1

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Nucleic acid (siRNA)
In vitro
CCCCCCSSCC
Evidence 2 Activity

Activity

Cell-penetrating Peptides

Assay & Model

Mice (Kunming species, 22 g, sex-matched)
Mice (Kunming species, 22 g, sex-matched)

Source & Reference

CPPsite3.0
CPPsite3

Other

Natural residues Linear L
Phage Display
Gamma-aminobutyric acid (GABA)
In vivo
CCCCCCSSCC
Additional Detail Fields 1 fields
CCCCCCSSCC