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Peptide record

TPDB61123

TD-34 Cell-penetrating Peptides standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB61123
TD-34
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 11-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
ACSSKKSKHCG
Physicochemical Analysis
C44H78N16O15S2
RNDEQILMFPTWYV
KS
1135.32
9.80
4
0
1
+3
3.68
-0.991
9.09
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
125
11.01
5
Residue Composition
number
1
A
0
R
0
N
0
D
2
C
0
E
0
Q
1
G
1
H
0
I
0
L
3
K
0
M
0
F
0
P
3
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 1 H: 1 I: 0 L: 0 K: 3 M: 0 F: 0 P: 0 S: 3 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
11
C44H78N16O15S2
1135.32
9.80
+3
3.68
-0.991
Free
L
Cationic
Cyclic
Free
N[C@@H](CCCCN)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Abdominal Skin From Male Kunming (Km) Mice

Assay & Model

Male Kunming (KM) mice
Male Kunming (KM) mice

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Cyclic L Cationic
Synthetic
Triptolide (TP)
In vitro and in vivo
CHHHHHHHTSCCCCCCC
Additional Detail Fields 1 fields
CHHHHHHHTSCCCCCCC