TPDB

3D PDB MODEL

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TPDB ID TPDB61092

Activity

Cell-penetrating Peptides

Activity_category_statistics

Delivery and barrier-penetrating peptides

Database_Source

CPPsite3.0

Sequence_Type

standard

Has_Modification No

Description A 25-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.

Sequence

ACLTFDHYWKQLTSMINIPEGKTAT

FASTA

>TPDB61092|Cell-penetrating Peptides|length=25
ACLTFDHYWKQLTSMINIPEGKTAT

Formula C129H198N32O38S2

Absent Amino Acids RV

Common Amino Acids T

Mass 2869.30

PI 7.15

Basic Residues 3

Acidic Residues 2

Hydrophobic Residues 10

Net Charge +0

Boman Index 1.87

Hydrophobicity -0.216

Aliphatic Index 70.40

Half Life

Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 6990

Absorbance 280nm 243.61

Polar Residues 9

number

2

A

0

R

1

N

1

D

1

C

1

E

1

Q

1

G

1

H

2

I

2

L

2

K

1

M

1

F

1

P

1

S

4

T

1

W

1

Y

0

V

Amino Acid Distribution

A: 2 R: 0 N: 1 D: 1 C: 1 E: 1 Q: 1 G: 1 H: 1 I: 2 L: 2 K: 2 M: 1 F: 1 P: 1 S: 1 T: 4 W: 1 Y: 1 V: 0

Length

25

Formula

C129H198N32O38S2

Mass

2869.30

PI

7.15

Net Charge

+0

Boman Index

1.87

Hydrophobicity

-0.216

Evidence 1 Activity

Source & Reference

Database Source CPPsite3.0

Other

Source Activity Label	Source Definition
Cell-penetrating Peptides	CPPsite3.0 experimentally validated cell-penetrating peptide annotation.