TPDB

3D PDB MODEL

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TPDB ID TPDB61091

Activity

Cell-penetrating Peptides

Activity_category_statistics

Delivery and barrier-penetrating peptides

Database_Source

CPPsite3.0

Sequence_Type

standard

Has_Modification No

Description A 23-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.

Sequence

ACLTFDHYWKQLTSMINIPEGKR

FASTA

>TPDB61091|Cell-penetrating Peptides|length=23
ACLTFDHYWKQLTSMINIPEGKR

Formula C124H191N33O34S2

Absent Amino Acids V

Common Amino Acids ILKT

Mass 2752.20

PI 8.86

Basic Residues 4

Acidic Residues 2

Hydrophobic Residues 9

Net Charge +1

Boman Index 2.57

Hydrophobicity -0.448

Aliphatic Index 72.17

Half Life

Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 6990

Absorbance 280nm 253.98

Polar Residues 7

number

1

A

1

R

1

N

1

D

1

C

1

E

1

Q

1

G

1

H

2

I

2

L

2

K

1

M

1

F

1

P

1

S

2

T

1

W

1

Y

0

V

Amino Acid Distribution

A: 1 R: 1 N: 1 D: 1 C: 1 E: 1 Q: 1 G: 1 H: 1 I: 2 L: 2 K: 2 M: 1 F: 1 P: 1 S: 1 T: 2 W: 1 Y: 1 V: 0

Length

23

Formula

C124H191N33O34S2

Mass

2752.20

PI

8.86

Net Charge

+1

Boman Index

2.57

Hydrophobicity

-0.448

Evidence 1 Activity

Source & Reference

Database Source CPPsite3.0

Other

Source Activity Label	Source Definition
Cell-penetrating Peptides	CPPsite3.0 experimentally validated cell-penetrating peptide annotation.