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Peptide record

TPDB61073

WRAP2 Cell-penetrating Peptides standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB61073
WRAP2
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 16-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: Nanoparticles
Sequence
AAWRAWRAAWRAWRAA
Physicochemical Analysis
C92H130N32O17
NDCEQGHILKMFPSTYV
A
1956.25
12.88
4
0
12
+4
-5.52
-0.450
50.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
22000
1124.60
0
Residue Composition
number
8
A
4
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
4
W
0
Y
0
V
Amino Acid Distribution
A: 8 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 4 Y: 0 V: 0
Chemical Descriptors
16
C92H130N32O17
1956.25
12.88
+4
-5.52
-0.450
Free
Nanoparticles
L
Amphipathic
Linear
Free
N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)NCC(=O)NCC(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

U87, Kb, MCF7, Huh7, Neuro2A, Cmt93, Ht29, Rm1 And MDA-MB-231 Cells,

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Synthetic
siRNA
Not efficient siRNA cellular delivery
In vitro
CCTTTTTTTC
Additional Detail Fields 1 fields
CCTTTTTTTC