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Peptide record

TPDB61070

MTS–ACHK₆HC Cell-penetrating Peptides standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB61070
MTS–ACHK₆HC
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 23-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation N-terminal: Acetylation
Sequence
Ac-AAVLLPVLLAAPACHKKKKKKHC-NH2
Physicochemical Analysis
C113H199N33O24S2
RNDEQGIMFSTWY
K
2468.15
10.54
8
0
11
+6
5.33
0.200
114.78
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
125
5.06
2
Residue Composition
number
5
A
0
R
0
N
0
D
2
C
0
E
0
Q
0
G
2
H
0
I
4
L
6
K
0
M
0
F
2
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 5 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 2 I: 0 L: 4 K: 6 M: 0 F: 0 P: 2 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
23
C113H199N33O24S2
2468.15
10.54
+6
5.33
0.200
Amidation
L
Amphiphilic
Linear
Acetylation
N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Nih/3 T3 And HeLa Cell Lines

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphiphilic
Synthetic
Plasmid DNA pSF-CMV-SEAP (OG105)
In vitro
CCTTCHHHHTTCCC
Additional Detail Fields 1 fields
CCTTCHHHHTTCCC