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Peptide record

TPDB61068

SN50 Cell-penetrating Peptides standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB61068
SN50
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 26-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
Sequence
AAVALLPAVLLALLAPVQRKRQKLMP
Physicochemical Analysis
C129H230N36O29S1
NDCEGHIFSTWY
L
2781.53
12.42
4
0
17
+4
1.15
0.896
161.54
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
6
A
2
R
0
N
0
D
0
C
0
E
2
Q
0
G
0
H
0
I
7
L
2
K
1
M
0
F
3
P
0
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 6 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 0 H: 0 I: 0 L: 7 K: 2 M: 1 F: 0 P: 3 S: 0 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
26
C129H230N36O29S1
2781.53
12.42
+4
1.15
0.896
L
Linear
N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

LE-II cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
In vitro
CCCSSGGGTTTTCSSSHHHHTTTCCC
Additional Detail Fields 1 fields
CCCSSGGGTTTTCSSSHHHHTTTCCC