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Peptide record

TPDB61065

PN29 (SEQ ID NO: 47) Cell-penetrating Peptides standard
28 amino acids
Basic Information
3D PDB MODEL
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TPDB61065
PN29 (SEQ ID NO: 47)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 28-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
AAVALLPAVLLALLAPSGASGLDKRDYV-NH2
Physicochemical Analysis
C127H214N32O36
NCEQHIMFTW
AL
2765.29
6.83
2
2
18
-0
-0.40
1.054
153.57
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
1490
53.88
3
Residue Composition
number
7
A
1
R
0
N
2
D
0
C
0
E
0
Q
2
G
0
H
0
I
7
L
1
K
0
M
0
F
2
P
2
S
0
T
0
W
1
Y
3
V
Amino Acid Distribution
A: 7 R: 1 N: 0 D: 2 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 7 K: 1 M: 0 F: 0 P: 2 S: 2 T: 0 W: 0 Y: 1 V: 3
Chemical Descriptors
28
C127H214N32O36
2765.29
6.83
-0
-0.40
1.054
Amidation
L
Linear
Free
N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)O.CC(C)C
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

9 L/LacZ cells

Source & Reference

CPPsite3.0
CPPsite3
US 20060035815

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Nucleic acid (siRNA)
In vitro
CCCCCTTTGGGGTSCCTTTSSSCCSSCC
Additional Detail Fields 1 fields
CCCCCTTTGGGGTSCCTTTSSSCCSSCC