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Peptide record

TPDB61064

PN365 (SEQ ID NO: 45) Cell-penetrating Peptides standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB61064
PN365 (SEQ ID NO: 45)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 22-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
AAVALLPAVLLALLAPRRRRRR-NH2
Physicochemical Analysis
C110H202N40O23
NDCEQGHIKMFSTWY
ARL
2453.07
13.10
6
0
14
+6
1.52
0.536
160.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
6
A
6
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
6
L
0
K
0
M
0
F
2
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 6 R: 6 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 6 K: 0 M: 0 F: 0 P: 2 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
22
C110H202N40O23
2453.07
13.10
+6
1.52
0.536
Amidation
L
Linear
Free
N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)[C@@H]1OOC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]2N(C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]3[N@]1CCC3)C)C(C)C)CC(C)C)CC(C)C)C)CC(C)C)CC(C)C)C)CCC2)CCCN=C)CCCN=C)CCCN=C)CCCN=C)CCCN=C)CCCN=C
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

9 L/LacZ cells

Source & Reference

CPPsite3.0
CPPsite3
US 20060035815

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Nucleic acid (siRNA)
In vitro
CCSCCTTTGGGGTCCCTTSCCC
Additional Detail Fields 1 fields
CCSCCTTTGGGGTCCCTTSCCC