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Peptide record

TPDB61052

NTCI (cSN50.1) Cell-penetrating Peptides standard
33 amino acids
Basic Information
3D PDB MODEL
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TPDB61052
NTCI (cSN50.1)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 33-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: FITC-labelled
Sequence
AAVALLPAVLLALLAGGKGGPCVQRKRQKLMPC
Physicochemical Analysis
C149H264N44O36S3
NDEHIFSTWY
L
3344.19
10.82
5
0
17
+5
1.70
0.691
127.27
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
125
3.74
4
Residue Composition
number
6
A
2
R
0
N
0
D
2
C
0
E
2
Q
4
G
0
H
0
I
7
L
3
K
1
M
0
F
3
P
0
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 6 R: 2 N: 0 D: 0 C: 2 E: 0 Q: 2 G: 4 H: 0 I: 0 L: 7 K: 3 M: 1 F: 0 P: 3 S: 0 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
33
C149H264N44O36S3
3344.19
10.82
+5
1.70
0.691
Free
FITC-labelled
L
Linear
Free
N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)NCC(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Assay & Model

8 –10-week-old C57BL/6 mice
8 –10-week-old C57BL/6 mice

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
FITC dye
Cytoplasm
In vivo
CCCSSHHHHHHHHHHHHSSSCCTTHHHHTTCCC
Additional Detail Fields 1 fields
CCCSSHHHHHHHHHHHHSSSCCTTHHHHTTCCC