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Peptide record

TPDB61050

PN225 (SEQ ID NO: 51) Cell-penetrating Peptides standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB61050
PN225 (SEQ ID NO: 51)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 27-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
AAVACRICMRNFSTRQARRNHRRRHRR-NH2
Physicochemical Analysis
C135H236N64O33S3
DEGLKPWY
R
3379.95
12.77
12
0
8
+10
8.95
-1.400
40.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
125
3.70
7
Residue Composition
number
4
A
10
R
2
N
0
D
2
C
0
E
1
Q
0
G
2
H
1
I
0
L
0
K
1
M
1
F
0
P
1
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 4 R: 10 N: 2 D: 0 C: 2 E: 0 Q: 1 G: 0 H: 2 I: 1 L: 0 K: 0 M: 1 F: 1 P: 0 S: 1 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
27
C135H236N64O33S3
3379.95
12.77
+10
8.95
-1.400
Amidation
L
Linear
Free
N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

9 L/LacZ cells

Source & Reference

CPPsite3.0
CPPsite3
US 20060035815

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Nucleic acid (siRNA)
In vitro
CCCCCCCSSSCCCCTTTTTCSCSCC
Additional Detail Fields 1 fields
CCCCCCCSSSCCCCTTTTTCSCSCC