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Peptide record

TPDB61006

ACE inhibitor ACE inhibitors Antidiabetic Neuropeptide standard
3 amino acids
Basic Information
3D PDB MODEL
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TPDB61006
ACE inhibitor
ACE inhibitors Antidiabetic Neuropeptide
Cardiometabolic peptides Neuroactive peptides
Peptipedia
standard
No
A 3-aa standard natural multi-activity (ACE inhibitors, Antidiabetic, and Neuropeptide) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
YPG
Physicochemical Analysis
C16H21N3O5
ARNDCEQHILKMFSTWV
GPY
335.36
5.94
0
0
1
-0
-0.48
-1.100
0.00
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
1490
444.30
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
0
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
3
C16H21N3O5
335.36
5.94
-0
-0.48
-1.100
335.3542
335.1476
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
23.44 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Wu J., Aluko R. E., Nakai S.
Structural requirements of angiotensin I-converting enzyme inhibitory activity: quantitative structure-activity relationship study of di- and tripeptides. J. Agric. Food Chem., 54, 732-738, 2006
2006
Journal

Other

3
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N1[C@@]([H])(CCC1)C(=O)NCC(=O)O InChI=1S/C16H21N3O5/c17-12(8-10-3-5-11(20)6-4-10)16(24)19-7-1-2-13(19)15(23)18-9-14(21)22/h3-6,12-13,20H,1-2,7-9,17H2,(H,18,23)(H,21,22)/t12-,13-/m0/s1 InChIKey: SZEIFUXUTBBQFQ-STQMWFEESA-N Inhibitor of alpha-glucosidase (EC 3.2.1.20) according to the BIOPEP-UWM database of bioactive peptide (ID 9066)
Additional Detail Fields 1 fields
3