TPDB

3D PDB MODEL

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TPDB ID TPDB60929

Peptide_Name

Leumorphin

Activity

Neuropeptide

Activity_category_statistics

Neuroactive peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 29-aa standard natural neuropeptide peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

YGGFLRRQFKVVTRSQEDPNAYSGELFDA

FASTA

>TPDB60929|Neuropeptide|length=29
YGGFLRRQFKVVTRSQEDPNAYSGELFDA

Formula C150H224N42O46

Absent Amino Acids CHIMW

Common Amino Acids RGF

Mass 3351.68

PI 7.05

Basic Residues 4

Acidic Residues 4

Hydrophobic Residues 11

Net Charge +0

Boman Index 5.79

Hydrophobicity -0.745

Aliphatic Index 53.79

Half Life

Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min

Extinction Coefficient Cystines 2980

Absorbance 280nm 88.91

Polar Residues 8

number

2

A

3

R

1

N

2

D

0

C

2

E

2

Q

3

G

0

H

0

I

2

L

1

K

0

M

3

F

1

P

2

S

1

T

0

W

2

Y

2

V

Amino Acid Distribution

A: 2 R: 3 N: 1 D: 2 C: 0 E: 2 Q: 2 G: 3 H: 0 I: 0 L: 2 K: 1 M: 0 F: 3 P: 1 S: 2 T: 1 W: 0 Y: 2 V: 2

Length

29

Formula

C150H224N42O46

Mass

3351.68

PI

7.05

Net Charge

+0

Boman Index

5.79

Hydrophobicity

-0.745

Evidence 1 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Delta-type opioid receptor

Receptor Organisms Homo sapiens

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Homo sapiens

Family Opioid

Receptor Lengths 372

Receptor Ligands NP08081 NP08163 NP08168 NP08174 NP08239 NP07973 NP08005 NP08011 NP08027 NP08034 NP08040 NP08114 NP08068 NP08075 NP08123 NP08130 NP08247 NP08092

Family

Opioid

Receptor_Lengths

372

Receptor_Ligands

NP08081 NP08163 NP08168 NP08174 NP08239 NP07973 NP08005 NP08011 NP08027 NP08034 NP08040 NP08114 NP08068 NP08075 NP08123 NP08130 NP08247 NP08092