Back to search

Peptide record

TPDB59947

Corticotropin Neuropeptide standard
39 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB59947
Corticotropin
Neuropeptide
Neuroactive peptides
Peptipedia
standard
No
A 39-aa standard natural neuropeptide peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
SYSMEHFRWGKPVGKKRRPVKVYPNVAENESAEAFPLEF
Physicochemical Analysis
C210H315N57O57S1
DCQIT
E
4582.22
9.82
8
5
15
+2
12.36
-0.862
47.44
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
8480
185.06
7
Residue Composition
number
3
A
3
R
2
N
0
D
0
C
5
E
0
Q
2
G
1
H
0
I
1
L
4
K
1
M
3
F
4
P
3
S
0
T
1
W
2
Y
4
V
Amino Acid Distribution
A: 3 R: 3 N: 2 D: 0 C: 0 E: 5 Q: 0 G: 2 H: 1 I: 0 L: 1 K: 4 M: 1 F: 3 P: 4 S: 3 T: 0 W: 1 Y: 2 V: 4
Chemical Descriptors
39
C210H315N57O57S1
4582.22
9.82
+2
12.36
-0.862
Evidence Records 2 records
Evidence 1 Activity

Activity

Neuropeptide

Target

Adrenocorticotropic hormone receptor Melanocortin receptor 3 Melanocortin receptor 4 Melanocortin receptor 5 Melanocyte-stimulating hormone receptor
Mus musculus Mus musculus Mus musculus Mus musculus Mus musculus

Source & Reference

NA
NeuroPepV2

Other

Mus musculus
POMC
296 323 332 325 315
NP08986 NP08974 NP08986 NP09089 NP09114 NP09139 NP08974 NP08986 NP09089 NP09114 NP09139 NP08974 NP08986 NP09089 NP09114 NP09139 NP08974 NP08986 NP09089 NP09114 NP09139
Evidence 2 Activity

Activity

Neuropeptide

Target

Melanocortin receptor 3 Melanocortin receptor 4 Melanocortin receptor 5
Rattus norvegicus Rattus norvegicus Rattus norvegicus

Source & Reference

NA
NeuroPepV2

Other

Rattus norvegicus
POMC
323 332 325
NP08992 NP09095 NP09119 NP09142 NP08102 NP08992 NP09095 NP09119 NP09142 NP08102 NP08992 NP09095 NP09119 NP09142 NP08102
Additional Detail Fields 3 fields
POMC
296 323 332 325 315
NP08986 NP08974 NP09089 NP09114 NP09139 NP08992 NP09095 NP09119 NP09142 NP08102