TPDB

3D PDB MODEL

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TPDB ID TPDB59550

Peptide_Name

C-flanking peptide of NPY

Activity

Neuropeptide

Activity_category_statistics

Neuroactive peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 30-aa standard natural neuropeptide peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

SSPETLISDLLMRESTENVPRTRLEDPAMW

FASTA

>TPDB59550|Neuropeptide|length=30
SSPETLISDLLMRESTENVPRTRLEDPAMW

Formula C148H241N41O51S2

Absent Amino Acids CQGHKFY

Common Amino Acids ELS

Mass 3474.91

PI 4.13

Basic Residues 3

Acidic Residues 6

Hydrophobic Residues 10

Net Charge -3

Boman Index 10.72

Hydrophobicity -0.650

Aliphatic Index 78.00

Half Life

Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 5500

Absorbance 280nm 158.28

Polar Residues 8

number

1

A

3

R

1

N

2

D

0

C

4

E

0

Q

0

G

0

H

1

I

4

L

0

K

2

M

0

F

3

P

4

S

3

T

1

W

0

Y

1

V

Amino Acid Distribution

A: 1 R: 3 N: 1 D: 2 C: 0 E: 4 Q: 0 G: 0 H: 0 I: 1 L: 4 K: 0 M: 2 F: 0 P: 3 S: 4 T: 3 W: 1 Y: 0 V: 1

Length

30

Formula

C148H241N41O51S2

Mass

3474.91

PI

4.13

Net Charge

-3

Boman Index

10.72

Hydrophobicity

-0.650

Evidence 1 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Prolactin-releasing peptide receptor Probable G-protein coupled receptor 83 Neuropeptide Y receptor type 1 Neuropeptide Y receptor type 2 Neuropeptide Y receptor type 4 Neuropeptide Y receptor type 5 Putative neuropeptide Y receptor type 6 Neuropeptide Y receptor type 4-2

Receptor Organisms Homo sapiens Homo sapiens Homo sapiens Homo sapiens Homo sapiens Homo sapiens Homo sapiens Homo sapiens

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Homo sapiens

Family NPY

Receptor Lengths 370 423 384 381 375 445 290 375

Receptor Ligands NP07551 NP07607 NP08561 NP08566 NP08567 NP06204 NP06208 NP07551 NP07607 NP07551 NP07607 NP07652 NP07689 NP07695 NP07718 NP07719 NP07720 NP07551 NP07607 NP07652 NP07689 NP07695 NP07718 NP07719 NP07720 NP07551 NP07607 NP07652 NP07689 NP07695 NP07718 NP07719 NP07720 NP07551 NP07607 NP07652 NP07689 NP07695 NP07718 NP07719 NP07720 NP07551 NP07607 NP07652 NP07689 NP07695 NP07718 NP07719 NP07720 NP07551 NP07607 NP07652 NP07689 NP07695 NP07718 NP07719 NP07720

Family

NPY

Receptor_Lengths

370 423 384 381 375 445 290

Receptor_Ligands

NP07551 NP07607 NP08561 NP08566 NP08567 NP06204 NP06208 NP07652 NP07689 NP07695 NP07718 NP07719 NP07720