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Peptide record

TPDB57824

Gonadoliberin-1 Neuropeptide standard

10 amino acids

3D PDB MODEL

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TPDB ID TPDB57824

Peptide_Name

Gonadoliberin-1

Activity

Neuropeptide

Activity_category_statistics

Neuroactive peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 10-aa standard natural neuropeptide peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

QHWSYGLRPG

FASTA

>TPDB57824|Neuropeptide|length=10
QHWSYGLRPG

Formula C55H77N17O14

Absent Amino Acids ANDCEIKMFTV

Common Amino Acids G

Mass 1200.32

PI 9.88

Basic Residues 2

Acidic Residues 0

Hydrophobic Residues 3

Net Charge +1

Boman Index -0.40

Hydrophobicity -1.280

Aliphatic Index 39.00

Half Life

Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour

Extinction Coefficient Cystines 6990

Absorbance 280nm 582.34

Polar Residues 3

number

Amino Acid Distribution

A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 2 H: 1 I: 0 L: 1 K: 0 M: 0 F: 0 P: 1 S: 1 T: 0 W: 1 Y: 1 V: 0

Length

Formula

C55H77N17O14

Mass

1200.32

9.88

Net Charge

Boman Index

-0.40

Hydrophobicity

-1.280

Evidence 1 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Gonadotropin-releasing hormone receptor

Receptor Organisms Homo sapiens

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Homo sapiens

Family GnRH

Receptor Lengths 328

Receptor Ligands NP04507 NP04569 NP04634 NP04522 NP04592 NP04653

Evidence 2 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Lithobates catesbeianus

Family GnRH

Evidence 3 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Gonadotropin-releasing hormone receptor

Receptor Organisms Macaca mulatta

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Macaca mulatta

Family GnRH

Receptor Lengths 59

Receptor Ligands NP04509 NP04571 NP04636 NP04524 NP04595 NP04655

Evidence 4 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Mesocricetus auratus

Family GnRH

Evidence 5 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Gonadotropin-releasing hormone receptor

Receptor Organisms Mus musculus

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Mus musculus

Family GnRH

Receptor Lengths 327

Receptor Ligands NP04574 NP04639 NP04680

Evidence 6 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Gonadotropin-releasing hormone receptor

Receptor Organisms Sus scrofa

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Sus scrofa

Family GnRH

Receptor Lengths 328

Receptor Ligands NP04642 NP04578 NP04514

Evidence 7 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Gonadotropin-releasing hormone receptor

Receptor Organisms Rattus norvegicus

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Rattus norvegicus

Family GnRH

Receptor Lengths 327

Receptor Ligands NP04625 NP04579 NP04643 NP04681 NP04682 NP04649

Evidence 8 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Gonadotropin-releasing hormone receptor

Receptor Organisms Ovis aries

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Ovis aries

Family GnRH

Receptor Lengths 328

Receptor Ligands NP04644 NP04580 NP04515

Evidence 9 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Tupaia belangeri

Family GnRH

Evidence 10 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Xenopus laevis

Family GnRH

Family

GnRH

Receptor_Lengths

328 59 327

Receptor_Ligands

NP04507 NP04569 NP04634 NP04522 NP04592 NP04653 NP04509 NP04571 NP04636 NP04524 NP04595 NP04655 NP04574 NP04639 NP04680 NP04642 NP04578 NP04514 NP04625 NP04579 NP04643 NP04681 NP04682 NP04649 NP04644 NP04580 NP04515