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Peptide record

TPDB57814

Gonadoliberin II Gonadoliberin-2 Neuropeptide standard

10 amino acids

3D PDB MODEL

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TPDB ID TPDB57814

Peptide_Name

Gonadoliberin II Gonadoliberin-2

Activity

Neuropeptide

Activity_category_statistics

Neuroactive peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 10-aa standard natural neuropeptide peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

QHWSHGWYPG

FASTA

>TPDB57814|Neuropeptide|length=10
QHWSHGWYPG

Formula C60H71N17O14

Absent Amino Acids ARNDCEILKMFTV

Common Amino Acids GHW

Mass 1254.33

PI 7.92

Basic Residues 2

Acidic Residues 0

Hydrophobic Residues 3

Net Charge +0

Boman Index -1.54

Hydrophobicity -1.620

Aliphatic Index 0.00

Half Life

Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour

Extinction Coefficient Cystines 12490

Absorbance 280nm 995.75

Polar Residues 3

number

Amino Acid Distribution

A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 2 H: 2 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 1 T: 0 W: 2 Y: 1 V: 0

Length

Formula

C60H71N17O14

Mass

1254.33

7.92

Net Charge

Boman Index

-1.54

Hydrophobicity

-1.620

Evidence 1 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Carassius auratus

Family GnRH

Evidence 2 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Alligator mississippiensis

Family GnRH

Evidence 3 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Gallus gallus

Family GnRH

Evidence 4 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Gonadotropin-releasing hormone II receptor

Receptor Organisms Clarias gariepinus

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Clarias gariepinus

Family GnRH

Receptor Lengths 379

Receptor Ligands NP04497 NP04499 NP04504 NP04520 NP04565 NP04631 NP04588 NP04650

Evidence 5 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Clupea pallasii

Family GnRH

Evidence 6 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Dicentrarchus labrax

Family GnRH

Evidence 7 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Haplochromis burtoni

Family GnRH

Evidence 8 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Gonadotropin-releasing hormone receptor Putative gonadotropin-releasing hormone II receptor

Receptor Organisms Homo sapiens Homo sapiens

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Homo sapiens

Family GnRH

Receptor Lengths 328 292

Receptor Ligands NP04507 NP04569 NP04634 NP04522 NP04592 NP04653 NP04522 NP04592 NP04653

Evidence 9 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Hydrolagus colliei

Family GnRH

Evidence 10 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Lithobates catesbeianus

Family GnRH

Evidence 11 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Gonadotropin-releasing hormone receptor Gonadotropin-releasing hormone II receptor

Receptor Organisms Macaca mulatta Macaca mulatta

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Macaca mulatta

Family GnRH

Receptor Lengths 59 379

Receptor Ligands NP04509 NP04571 NP04636 NP04524 NP04595 NP04655 NP04524 NP04595 NP04655

Evidence 12 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Morone saxatilis

Family GnRH

Evidence 13 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Oncorhynchus mykiss

Family GnRH

Evidence 14 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Oryzias latipes

Family GnRH

Evidence 15 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Rutilus rutilus

Family GnRH

Evidence 16 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Sparus aurata

Family GnRH

Evidence 17 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Squalus acanthias

Family GnRH

Evidence 18 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Suncus murinus

Family GnRH

Evidence 19 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Tupaia belangeri

Family GnRH

Evidence 20 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Verasper moseri

Family GnRH

Family

GnRH

Receptor_Lengths

379 328 292 59

Receptor_Ligands

NP04497 NP04499 NP04504 NP04520 NP04565 NP04631 NP04588 NP04650 NP04507 NP04569 NP04634 NP04522 NP04592 NP04653 NP04509 NP04571 NP04636 NP04524 NP04595 NP04655