Peptide record

TPDB56422

dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) – Wheylin-1 Neuropeptide iDPPIV standard
2 amino acids
Basic Information
3D PDB MODEL
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TPDB56422
dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) – Wheylin-1
Neuropeptide iDPPIV
Cardiometabolic peptides Neuroactive peptides
Peptipedia iDPPIV
standard
No
A 2-aa standard natural multi-activity (Neuropeptide and iDPPIV) peptide sequence curated from Peptipedia and iDPPIV, with an available 3D structural model.
Sequence
MH
Physicochemical Analysis
C11H18N4O3S1
ARNDCEQGILKFPSTWYV
HM
286.35
7.85
1
0
1
+0
0.73
-0.650
0.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
0
I
0
L
0
K
1
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 0 L: 0 K: 0 M: 1 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
2
C11H18N4O3S1
286.35
7.85
+0
0.73
-0.650
286.3510
286.1096
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
iDPPIV
0.00 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Lan V. T. T., Ito K., Ohno M., Motoyama T., Ito S., Kawarasaki Y.
Analyzing a dipeptide library to identify human dipeptidyl peptidase IV inhibitor. Food Chemistry 175, 66-73, 2015
2015
Journal

Other

2
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@H](CCSC)C(=O)N[C@@H](CC1=C[N]([H])C=N1)C(=O)O InChI=1S/C11H18N4O3S/c1-19-3-2-8(12)10(16)15-9(11(17)18)4-7-5-13-6-14-7/h5-6,8-9H,2-4,12H2,1H3,(H,13,14)(H,15,16)(H,17,18)/t8-,9-/m0/s1 InChIKey=MWAYJIAKVUBKKP-IUCAKERBSA-N Anxiolytic-like peptide according to the BIOPEP-UWM database of bioactive peptides (ID 10111)
Additional Detail Fields 1 fields
2