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Peptide record

TPDB55804

Islet amyloid polypeptide non-cyclic Amylin Blood-Brain Barrier Neuropeptide standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB55804
Islet amyloid polypeptide non-cyclic Amylin
Blood-Brain Barrier Neuropeptide
Delivery and barrier-penetrating peptides Neuroactive peptides
BBPpredict Peptipedia
standard
No
A 37-aa standard natural multi-activity (Blood-Brain Barrier and Neuropeptide) peptide sequence curated from BBPpredict and Peptipedia, with an available 3D structural model.
Sequence
KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
Physicochemical Analysis
C167H273N51O54S2
DEHIMW
N
3923.43
9.79
3
0
12
+3
3.08
-0.249
73.78
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
1615
41.16
18
Residue Composition
number
3
A
2
R
6
N
0
D
2
C
0
E
1
Q
2
G
0
H
0
I
4
L
1
K
0
M
1
F
3
P
3
S
5
T
0
W
1
Y
3
V
Amino Acid Distribution
A: 3 R: 2 N: 6 D: 0 C: 2 E: 0 Q: 1 G: 2 H: 0 I: 0 L: 4 K: 1 M: 0 F: 1 P: 3 S: 3 T: 5 W: 0 Y: 1 V: 3
Chemical Descriptors
37
C167H273N51O54S2
3923.43
9.79
+3
3.08
-0.249
Linear
Similarity
Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-Arg-Ser-Ser-Asn-Asn-Leu-Gly-Pro-Val-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr
Evidence Records 3 records
Evidence 1 Activity

Activity

Blood-Brain Barrier
23%

Assay & Model

Capillary depletion
Origin/Source
% capillary

Source & Reference

NA
B3Pdb

Other

synthetic,honey bee
Direct iodination
Evidence 2 Activity

Activity

Neuropeptide

Target

Calcitonin receptor
Mus musculus

Source & Reference

NA
NeuroPepV2

Other

Mus musculus
Calcitonin
533
NP01780 NP01825
Evidence 3 Activity

Activity

Neuropeptide

Target

Calcitonin receptor
Rattus norvegicus

Source & Reference

NA
NeuroPepV2

Other

Rattus norvegicus
Calcitonin
516
NP01782 NP01829
Additional Detail Fields 3 fields
Calcitonin
533 516
NP01780 NP01825 NP01782 NP01829