TPDB

3D PDB MODEL

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TPDB ID TPDB55797

Peptide_Name

Cholecystokinin-33

Activity

Neuropeptide

Activity_category_statistics

Neuroactive peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 33-aa standard natural neuropeptide peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

KAPSGRMSVLKNLQGLDPSHRISDRDYMGWMDF

FASTA

>TPDB55797|Neuropeptide|length=33
KAPSGRMSVLKNLQGLDPSHRISDRDYMGWMDF

Formula C165H259N49O49S3

Absent Amino Acids CET

Common Amino Acids DS

Mass 3809.35

PI 9.65

Basic Residues 6

Acidic Residues 4

Hydrophobic Residues 12

Net Charge +1

Boman Index 6.04

Hydrophobicity -0.755

Aliphatic Index 59.09

Half Life

Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min

Extinction Coefficient Cystines 6990

Absorbance 280nm 183.50

Polar Residues 7

number

1

A

3

R

1

N

4

D

0

C

0

E

1

Q

3

G

1

H

1

I

3

L

2

K

3

M

1

F

2

P

4

S

0

T

1

W

1

Y

1

V

Amino Acid Distribution

A: 1 R: 3 N: 1 D: 4 C: 0 E: 0 Q: 1 G: 3 H: 1 I: 1 L: 3 K: 2 M: 3 F: 1 P: 2 S: 4 T: 0 W: 1 Y: 1 V: 1

Length

33

Formula

C165H259N49O49S3

Mass

3809.35

PI

9.65

Net Charge

+1

Boman Index

6.04

Hydrophobicity

-0.755

Evidence 1 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Cholecystokinin receptor type A Gastrin/cholecystokinin type B receptor

Receptor Organisms Rattus norvegicus Rattus norvegicus

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Rattus norvegicus

Family Gastrin/cholecystokinin

Receptor Lengths 444 452

Receptor Ligands NP03865 NP03900 NP03906 NP03920 NP03928 NP03974 NP03887 NP03865 NP03900 NP03906 NP03920 NP03928 NP03974 NP03813 NP04017 NP03887

Family

Gastrin/cholecystokinin

Receptor_Lengths

444 452

Receptor_Ligands

NP03865 NP03900 NP03906 NP03920 NP03928 NP03974 NP03887 NP03813 NP04017