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Peptide record

TPDB54895

Glucagon-like peptide 1(7-36) Blood-Brain Barrier Neuropeptide standard

30 amino acids

3D PDB MODEL

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TPDB ID TPDB54895

Peptide_Name

Glucagon-like peptide 1(7-36)

Activity

Blood-Brain Barrier Neuropeptide

Activity_category_statistics

Delivery and barrier-penetrating peptides Neuroactive peptides

Database_Source

BBPpredict Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 30-aa standard natural multi-activity (Blood-Brain Barrier and Neuropeptide) peptide sequence curated from BBPpredict and Peptipedia, with an available 3D structural model.

Sequence

HAEGTFTSDVSSYLEGQAAKEFIAWLVKGR

FASTA

>TPDB54895|Blood-Brain Barrier;Neuropeptide|length=30
HAEGTFTSDVSSYLEGQAAKEFIAWLVKGR

Formula C149H225N39O46

Absent Amino Acids NCMP

Common Amino Acids A

Mass 3298.66

PI 5.43

Basic Residues 4

Acidic Residues 4

Hydrophobic Residues 13

Net Charge -1

Boman Index 5.30

Hydrophobicity -0.230

Aliphatic Index 71.67

Half Life

Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour

Extinction Coefficient Cystines 6990

Absorbance 280nm 211.90

Polar Residues 7

number

Amino Acid Distribution

A: 4 R: 1 N: 0 D: 1 C: 0 E: 3 Q: 1 G: 3 H: 1 I: 1 L: 2 K: 2 M: 0 F: 2 P: 0 S: 3 T: 2 W: 1 Y: 1 V: 2

Length

Formula

C149H225N39O46

Mass

3298.66

5.43

Net Charge

-1

Boman Index

5.30

Hydrophobicity

-0.230

Evidence 1 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Bos taurus

Family Glucagon

Evidence 2 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Canis lupus familiaris

Family Glucagon

Evidence 3 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Cavia porcellus

Family Glucagon

Evidence 4 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Glucagon-like peptide 1 receptor

Receptor Organisms Homo sapiens

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Homo sapiens

Family Glucagon

Receptor Lengths 463

Receptor Ligands NP04305 NP04320 NP04332

Evidence 5 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Mesocricetus auratus

Family Glucagon

Evidence 6 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Glucagon-like peptide 1 receptor

Receptor Organisms Mus musculus

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Mus musculus

Family Glucagon

Receptor Lengths 463

Receptor Ligands NP04308 NP04322 NP04334

Evidence 7 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Octodon degus

Family Glucagon

Evidence 8 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Sus scrofa

Family Glucagon

Evidence 9 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Glucagon-like peptide 1 receptor

Receptor Organisms Rattus norvegicus

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Rattus norvegicus

Family Glucagon

Receptor Lengths 463

Receptor Ligands NP04311 NP04325 NP04337

Evidence 10 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Ovis aries

Family Glucagon

Family

Glucagon

Receptor_Lengths

463

Receptor_Ligands

NP04305 NP04320 NP04332 NP04308 NP04322 NP04334 NP04311 NP04325 NP04337