TPDB

3D PDB MODEL

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TPDB ID TPDB54805

Peptide_Name

Galanin Galanin peptides

Activity

Neuropeptide

Activity_category_statistics

Neuroactive peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 29-aa standard natural neuropeptide peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

GWTLNSAGYLLGPHAIDNHRSFSDKHGLT

FASTA

>TPDB54805|Neuropeptide|length=29
GWTLNSAGYLLGPHAIDNHRSFSDKHGLT

Formula C141H210N42O42

Absent Amino Acids CEQMV

Common Amino Acids GL

Mass 3165.47

PI 7.99

Basic Residues 5

Acidic Residues 2

Hydrophobic Residues 10

Net Charge +0

Boman Index 2.33

Hydrophobicity -0.521

Aliphatic Index 74.14

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 6990

Absorbance 280nm 220.82

Polar Residues 8

number

2

A

1

R

2

N

2

D

0

C

0

E

0

Q

4

G

3

H

1

I

4

L

1

K

0

M

1

F

1

P

3

S

2

T

1

W

1

Y

0

V

Amino Acid Distribution

A: 2 R: 1 N: 2 D: 2 C: 0 E: 0 Q: 0 G: 4 H: 3 I: 1 L: 4 K: 1 M: 0 F: 1 P: 1 S: 3 T: 2 W: 1 Y: 1 V: 0

Length

29

Formula

C141H210N42O42

Mass

3165.47

PI

7.99

Net Charge

+0

Boman Index

2.33

Hydrophobicity

-0.521

Evidence 1 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Galanin receptor type 1 Galanin receptor type 2 Galanin receptor type 3

Receptor Organisms Mus musculus Mus musculus Mus musculus

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Mus musculus

Family Galanin

Receptor Lengths 348 371 370

Receptor Ligands NP03767 NP03767 NP03793 NP10603 NP03767 NP10603

Evidence 2 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Galanin receptor type 1 Galanin receptor type 2 Galanin receptor type 3

Receptor Organisms Rattus norvegicus Rattus norvegicus Rattus norvegicus

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Rattus norvegicus

Family Galanin

Receptor Lengths 346 372 370

Receptor Ligands NP03771 NP03777 NP03778 NP03790 NP03771 NP03795 NP03777 NP03778 NP03790 NP10604 NP03771 NP03777 NP03778 NP03790 NP10604

Evidence 3 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Galanin receptor type 1 Galanin receptor type 2 Galanin receptor type 3

Receptor Organisms Rattus norvegicus Rattus norvegicus Rattus norvegicus

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Rattus norvegicus

Family Galanin

Receptor Lengths 346 372 370

Receptor Ligands NP03771 NP03777 NP03778 NP03790 NP03771 NP03795 NP03777 NP03778 NP03790 NP10604 NP03771 NP03777 NP03778 NP03790 NP10604

Family

Galanin

Receptor_Lengths

348 371 370 346 372

Receptor_Ligands

NP03767 NP03793 NP10603 NP03771 NP03777 NP03778 NP03790 NP03795 NP10604