TPDB

3D PDB MODEL

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TPDB ID TPDB54739

Peptide_Name

Cholecystokinin 5 Cholecystokinin-5

Activity

Neuropeptide

Activity_category_statistics

Neuroactive peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 5-aa standard natural neuropeptide peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

GWMDF

FASTA

>TPDB54739|Neuropeptide|length=5
GWMDF

Formula C31H38N6O8S1

Absent Amino Acids ARNCEQHILKPSTYV

Common Amino Acids DGMFW

Mass 654.74

PI 3.10

Basic Residues 0

Acidic Residues 1

Hydrophobic Residues 3

Net Charge -1

Boman Index -1.97

Hydrophobicity -0.020

Aliphatic Index 0.00

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 5500

Absorbance 280nm 840.03

Polar Residues 0

number

0

A

0

R

0

N

1

D

0

C

0

E

0

Q

1

G

0

H

0

I

0

L

0

K

1

M

1

F

0

P

0

S

0

T

1

W

0

Y

0

V

Amino Acid Distribution

A: 0 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 0 M: 1 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0

Length

5

Formula

C31H38N6O8S1

Mass

654.74

PI

3.10

Net Charge

-1

Boman Index

-1.97

Hydrophobicity

-0.020

Evidence 1 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Gastrin/cholecystokinin type B receptor

Receptor Organisms Sus scrofa

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Sus scrofa

Family Gastrin/cholecystokinin

Receptor Lengths 452

Receptor Ligands NP03890 NP03943 NP03864 NP03940 NP03948 NP03927 NP03919 NP03911 NP03905 NP03899 NP03973 NP03957 NP03934 NP03812 NP04016

Evidence 2 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Gastrin/cholecystokinin type B receptor

Receptor Organisms Bos taurus

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Bos taurus

Family Gastrin/cholecystokinin

Receptor Lengths 454

Receptor Ligands NP03854 NP03893 NP03901 NP03907 NP03913 NP03923 NP03930 NP03935 NP03944 NP03951 NP03964 NP03801 NP04005

Evidence 3 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Cholecystokinin receptor type A Gastrin/cholecystokinin type B receptor

Receptor Organisms Canis lupus familiaris Canis lupus familiaris

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Canis lupus familiaris

Family Gastrin/cholecystokinin

Receptor Lengths 428 453

Receptor Ligands NP03936 NP03945 NP03924 NP03914 NP03908 NP03902 NP03894 NP03965 NP03952 NP03931 NP03802 NP04006 NP03936 NP03945 NP03924 NP03914 NP03908 NP03902 NP03894 NP03965 NP03952 NP03931

Evidence 4 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Cholecystokinin receptor type A Gastrin/cholecystokinin type B receptor

Receptor Organisms Homo sapiens Homo sapiens

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Homo sapiens

Family Gastrin/cholecystokinin

Receptor Lengths 428 447

Receptor Ligands NP03809 NP03858 NP03896 NP03903 NP03909 NP03915 NP03925 NP03932 NP03937 NP03946 NP03954 NP03968 NP04013 NP04026 NP04029 NP04030 NP04031 NP03809 NP03858 NP03896 NP03903 NP03909 NP03915 NP03925 NP03932 NP03937 NP03946 NP03954 NP03968 NP04013 NP04026 NP04029 NP04030 NP04031

Evidence 5 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Macaca fascicularis

Family Gastrin/cholecystokinin

Family

Gastrin/cholecystokinin

Receptor_Lengths

452 454 428 453 447

Receptor_Ligands

NP03890 NP03943 NP03864 NP03940 NP03948 NP03927 NP03919 NP03911 NP03905 NP03899 NP03973 NP03957 NP03934 NP03812 NP04016 NP03854 NP03893 NP03901 NP03907 NP03913 NP03923 NP03930 NP03935 NP03944 NP03951 NP03964 NP03801 NP04005 NP03936 NP03945 NP03924 NP03914 NP03908 NP03902 NP03894 NP03965 NP03952 NP03931 NP03802 NP04006 NP03809 NP03858 NP03896 NP03903 NP03909 NP03915 NP03925 NP03932 NP03937 NP03946 NP03954 NP03968 NP04013 NP04026 NP04029 NP04030 NP04031