TPDB

3D PDB MODEL

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TPDB ID TPDB54580

Peptide_Name

Neuromedin-C

Activity

Neuropeptide

Activity_category_statistics

Neuroactive peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 10-aa standard natural neuropeptide peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

GSHWAVGHLM

FASTA

>TPDB54580|Neuropeptide|length=10
GSHWAVGHLM

Formula C49H71N15O12S1

Absent Amino Acids RNDCEQIKFPTY

Common Amino Acids GH

Mass 1094.26

PI 8.00

Basic Residues 2

Acidic Residues 0

Hydrophobic Residues 5

Net Charge +0

Boman Index -0.67

Hydrophobicity 0.280

Aliphatic Index 78.00

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 5500

Absorbance 280nm 502.62

Polar Residues 1

number

1

A

0

R

0

N

0

D

0

C

0

E

0

Q

2

G

2

H

0

I

1

L

0

K

1

M

0

F

0

P

1

S

0

T

1

W

0

Y

1

V

Amino Acid Distribution

A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 2 I: 0 L: 1 K: 0 M: 1 F: 0 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 1

Length

10

Formula

C49H71N15O12S1

Mass

1094.26

PI

8.00

Net Charge

+0

Boman Index

-0.67

Hydrophobicity

0.280

Evidence 1 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Alligator mississippiensis

Family Bombesin/neuromedin-B/ranatensin

Evidence 2 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names [Phe13]-bombesin receptor

Receptor Organisms Bombina orientalis

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Bombina orientalis

Family Bombesin/neuromedin-B/ranatensin

Receptor Lengths 392

Receptor Ligands NP01529 NP01556 NP01527 NP01516

Evidence 3 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Gallus gallus

Family Bombesin/neuromedin-B/ranatensin

Evidence 4 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Gastrin-releasing peptide receptor

Receptor Organisms Mus musculus

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Mus musculus

Family Bombesin/neuromedin-B/ranatensin

Receptor Lengths 384

Receptor Ligands NP01535 NP01562

Evidence 5 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Pelophylax ridibundus

Family Bombesin/neuromedin-B/ranatensin

Evidence 6 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Gastrin-releasing peptide receptor

Receptor Organisms Rattus norvegicus

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Rattus norvegicus

Family Bombesin/neuromedin-B/ranatensin

Receptor Lengths 384

Receptor Ligands NP01538 NP01565

Family

Bombesin/neuromedin-B/ranatensin

Receptor_Lengths

392 384

Receptor_Ligands

NP01529 NP01556 NP01527 NP01516 NP01535 NP01562 NP01538 NP01565