TPDB

3D PDB MODEL

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TPDB ID TPDB53470

Peptide_Name

Morphine-modulating neuropeptide B Neuropeptide FF

Activity

Neuropeptide

Activity_category_statistics

Neuroactive peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 8-aa standard natural neuropeptide peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

FLFQPQRF

FASTA

>TPDB53470|Neuropeptide|length=8
FLFQPQRF

Formula C54H75N13O11

Absent Amino Acids ANDCEGHIKMSTWYV

Common Amino Acids F

Mass 1082.27

PI 11.05

Basic Residues 1

Acidic Residues 0

Hydrophobic Residues 4

Net Charge +1

Boman Index -1.53

Hydrophobicity -0.113

Aliphatic Index 48.75

Half Life

Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min

Extinction Coefficient Cystines 0

Absorbance 280nm 0.00

Polar Residues 2

number

0

A

1

R

0

N

0

D

0

C

0

E

2

Q

0

G

0

H

0

I

1

L

0

K

0

M

3

F

1

P

0

S

0

T

0

W

0

Y

0

V

Amino Acid Distribution

A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 3 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0

Length

8

Formula

C54H75N13O11

Mass

1082.27

PI

11.05

Net Charge

+1

Boman Index

-1.53

Hydrophobicity

-0.113

Evidence 1 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Bos taurus

Family FMRFamide related peptide

Evidence 2 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Neuropeptide FF receptor 1 Neuropeptide FF receptor 2

Receptor Organisms Homo sapiens Homo sapiens

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Homo sapiens

Family FMRFamide related peptide

Receptor Lengths 430 522

Receptor Ligands NP03545 NP03550 NP03563 NP03568 NP03496 NP03540 NP03545 NP03550 NP03563 NP03568 NP03496 NP03540

Evidence 3 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Neuropeptide FF receptor 2

Receptor Organisms Mus musculus

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Mus musculus

Family FMRFamide related peptide

Receptor Lengths 417

Receptor Ligands NP03493 NP03537 NP03541

Evidence 4 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Neuropeptide FF receptor 1 Neuropeptide FF receptor 2

Receptor Organisms Rattus norvegicus Rattus norvegicus

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Rattus norvegicus

Family FMRFamide related peptide

Receptor Lengths 432 417

Receptor Ligands NP03494 NP03542 NP03494 NP03542

Evidence 5 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Bos taurus

Family

FMRFamide related peptide

Receptor_Lengths

430 522 417 432

Receptor_Ligands

NP03545 NP03550 NP03563 NP03568 NP03496 NP03540 NP03493 NP03537 NP03541 NP03494 NP03542